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Table 2 Clinical and laboratory findings of the admitted patients according to age (n = 373)

From: Pandemic 2009 H1N1 virus infection in children and adults: A cohort study at a single hospital throughout the epidemic

Age groups

0-15 y

(n = 217)

16-40 y

(n = 100)

41-64y

(n = 35)

≥ 65 y

(n = 21)

P

Clinical Characteristics

     

   Age, mean (y)

6.2 ± 3.7

25.2 ± 7

51.9 ± 6.7

74 ± 5

< 0.001

   Male/female

132/85

45/55

14/21

5/16

< 0.001

   Duration of fever (d)

     

Before admission

2.0 ± 1.9

2.0 ± 1.1

1.7 ± 1.5

1.5 ± 1.3

0.045

Total duration

2.3 ± 1.0

2.9 ± 1.3

3.0 ± 1.7

4.1 ± 3.0

< 0.01

   Oseltamivir, < 48 h*

205 (94)

89 (89)

29 (83)

15 (71)

NS

   Hospitalisation (d)

4.9 ± 1.5

5.4 ± 2.2

5.2 ± 2.9

8.8 ± 5.1

< 0.001

   Pneumonia

     

Number (%)

80 (37)

16 (16)

9 (29)

11 (52)

NS

Male/female

60/20

4/11

4/5

3/8

< 0.001

   Underlying diseases

17 (7.8)

15 (15)

15 (42.9)

16 (76.2)

< 0.001

Laboratory findings

     

   Haemoglobin (g/dL)

12.6 ± 0.9

13.5 ± 2.1

13.1 ± 1.6

12.9 ± 1.4

< 0.001

   Leukocyte (×109/L)

7.4 ± 3.6

6.4 ± 2.6

6.8 ± 2.8

7.6 ± 3.2

< 0.001

Neutrophil (%)

63 ± 19

66 ± 15

71 ± 14

64 ± 17

NS

Lymphocyte (%)

27 ± 17

23 ± 13

20 ± 12

24 ± 14

0.037

Monocyte (%)

9 ± 4

8 ± 4

8 ± 4

9 ± 4

NS

   Platelet (×109/L)

230 ± 59

202 ± 46

204 ± 51

198 ± 55

0.001

   CRP (mg/dL)

1.6 ± 2.0

2.4 ± 3.8

3.8 ± 4.6

6.1 ± 6.9

< 0.001

   ESR (mm/h)

17 ± 12

19 ± 17

37 ± 22

42 ± 19

< 0.001

  1. CRP; C-reactive protein, ESR; erythrocyte sedimentation rate. NS, statistically non-specific
  2. * Number (%) of patients who received oseltamivir treatment within 48 h of fever onset
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