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Table 1 Expression of IL-17RC protein in human tissues.

From: Expression of interleukin-17RC protein in normal human tissues

Figure number Age of donor Organ/tissue Cell type Anti-ICD Anti-ECD
1A/A' 27 Aorta Smooth muscle - -
1B/B' 59 Heart Myocardium + +
1C/C' 27 Lymphangioma Lymphatic endothelium + +++
1D/D' 56 Lung Small artery, endothelium +++ +++
1E/E' 49 Intestine Small vein, endothelium +++ ++
2A/A' Unknown Adrenal gland Cortex, glandular cell +++ ++
2B/B' Unknown Adrenal gland Medulla, glandular cell + +
2C/C' 59 Parathyroid Adenoma, glandular cell - ++
2D/D' 78 Pituitary Anterior, glandular cell + ++
2E/E' 48 Thyroid gland Glandular cell + +
3A/A' 81 Esophagus Squamous cell - +++
3B/B' 43 Stomach Antral mucosa, epithelium - -
3C/C' 53 Stomach Oxyntic mucosa, epithelium + ++
3D/D' 45 Small intestine Mucosa, epithelium - +
3E/E' 59 Colon Mucosa, epithelium - -
3F/F' 59 Anus Mucosa, squamous cell - +++
4A/A' 46 Breast Gland, epithelium - +++
4B/B' 55 Cervix Ectocervix, squamous cell - +++
4C/C' 60 Cervix Endocervix, epithelium - ++
4D/D' 49 Uterus Endometrium, secretory - -
4E/E' 52 Fallopian tube epithelium - +++
4F/F' 18 Ovary oocyte + +
5A/A' 72 Testis Seminiferous tubule ++ +
5B/B' 83 Epididymis epithelium ++ ++
5C/C' 56 Seminal vesicle epithelium + +
5D/D' 41 Prostate epithelium - +++
6A/A' 78 Brain Cerebral cortex, neuron - -
6B/B' 78 Brain Cerebellar cortex, purkinje/granular cell - -
6C/C' 78 Brain Ependymal cell - -
6D/D' 78 Hippocampus Neuron - -
6E/E' 78 Spinal cord Motor neuron + +
6F/F' 52 Intestine Autonomic ganglia + +
7A/A' 58 Liver Hepatocyte - -
7B/B' 69 Gallbladder Epithelium + ++
7C/C' 43 Pancreas Glandular cell - ++
7D/D' 65 Salivary gland, parotid Glandular cell +++ +++
8A/A' 62 Kidney Cortex, glomerulus +++ +++
8B/B' 91 Kidney Medulla, epithelium + +++
8C/C' 41 Bladder Transitional epithelium + +++
8D/D' 73 Lung Alveoli, epithelium + ++
8E/E' 73 Bronchus Epithelium - +++
9A/A' 60 Skin Squamous cell - ++
9B/B' 60 Subepidermis Glandular cell + +++
9C/C' 76 Lymph node Lymphatic cell - -
9D/D' 52 Spleen Lymphatic cell - -
9E/E' 32 Thymus Lymphatic cell - -
9F/F' 4 Tonsil Lymphatic cell - -
10A/A' 49 Skeletal muscle Skeletal muscle cell - +
10B/B' 52 Instestine Smooth muscle cell - -
10C/C' 55 Uterus Smooth muscle cell - -
10D/D' 39 Breast Adipocyte + +
10E/E' 62 Cartilage, articular Chondrocyte + -
10F/F' 62 Synovium Synovial cell ++ -
  1. The intensity of IL-17RC staining for a particular cell type in the tissues was graded in this way: - = no staining; + = weak; ++ = intermediate; +++ = strong. The vascular endothelium had intermediate to strong staining in most tissues.