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Table 1 Expression of IL-17RC protein in human tissues.

From: Expression of interleukin-17RC protein in normal human tissues

Figure number

Age of donor

Organ/tissue

Cell type

Anti-ICD

Anti-ECD

1A/A'

27

Aorta

Smooth muscle

-

-

1B/B'

59

Heart

Myocardium

+

+

1C/C'

27

Lymphangioma

Lymphatic endothelium

+

+++

1D/D'

56

Lung

Small artery, endothelium

+++

+++

1E/E'

49

Intestine

Small vein, endothelium

+++

++

2A/A'

Unknown

Adrenal gland

Cortex, glandular cell

+++

++

2B/B'

Unknown

Adrenal gland

Medulla, glandular cell

+

+

2C/C'

59

Parathyroid

Adenoma, glandular cell

-

++

2D/D'

78

Pituitary

Anterior, glandular cell

+

++

2E/E'

48

Thyroid gland

Glandular cell

+

+

3A/A'

81

Esophagus

Squamous cell

-

+++

3B/B'

43

Stomach

Antral mucosa, epithelium

-

-

3C/C'

53

Stomach

Oxyntic mucosa, epithelium

+

++

3D/D'

45

Small intestine

Mucosa, epithelium

-

+

3E/E'

59

Colon

Mucosa, epithelium

-

-

3F/F'

59

Anus

Mucosa, squamous cell

-

+++

4A/A'

46

Breast

Gland, epithelium

-

+++

4B/B'

55

Cervix

Ectocervix, squamous cell

-

+++

4C/C'

60

Cervix

Endocervix, epithelium

-

++

4D/D'

49

Uterus

Endometrium, secretory

-

-

4E/E'

52

Fallopian tube

epithelium

-

+++

4F/F'

18

Ovary

oocyte

+

+

5A/A'

72

Testis

Seminiferous tubule

++

+

5B/B'

83

Epididymis

epithelium

++

++

5C/C'

56

Seminal vesicle

epithelium

+

+

5D/D'

41

Prostate

epithelium

-

+++

6A/A'

78

Brain

Cerebral cortex, neuron

-

-

6B/B'

78

Brain

Cerebellar cortex, purkinje/granular cell

-

-

6C/C'

78

Brain

Ependymal cell

-

-

6D/D'

78

Hippocampus

Neuron

-

-

6E/E'

78

Spinal cord

Motor neuron

+

+

6F/F'

52

Intestine

Autonomic ganglia

+

+

7A/A'

58

Liver

Hepatocyte

-

-

7B/B'

69

Gallbladder

Epithelium

+

++

7C/C'

43

Pancreas

Glandular cell

-

++

7D/D'

65

Salivary gland, parotid

Glandular cell

+++

+++

8A/A'

62

Kidney

Cortex, glomerulus

+++

+++

8B/B'

91

Kidney

Medulla, epithelium

+

+++

8C/C'

41

Bladder

Transitional epithelium

+

+++

8D/D'

73

Lung

Alveoli, epithelium

+

++

8E/E'

73

Bronchus

Epithelium

-

+++

9A/A'

60

Skin

Squamous cell

-

++

9B/B'

60

Subepidermis

Glandular cell

+

+++

9C/C'

76

Lymph node

Lymphatic cell

-

-

9D/D'

52

Spleen

Lymphatic cell

-

-

9E/E'

32

Thymus

Lymphatic cell

-

-

9F/F'

4

Tonsil

Lymphatic cell

-

-

10A/A'

49

Skeletal muscle

Skeletal muscle cell

-

+

10B/B'

52

Instestine

Smooth muscle cell

-

-

10C/C'

55

Uterus

Smooth muscle cell

-

-

10D/D'

39

Breast

Adipocyte

+

+

10E/E'

62

Cartilage, articular

Chondrocyte

+

-

10F/F'

62

Synovium

Synovial cell

++

-

  1. The intensity of IL-17RC staining for a particular cell type in the tissues was graded in this way: - = no staining; + = weak; ++ = intermediate; +++ = strong. The vascular endothelium had intermediate to strong staining in most tissues.