Table 3 Univariate predictors of disease activity grade
| Â | Sensitivity | Specificity | PPV | NPV | P value |
|---|---|---|---|---|---|
Anti-CCP present | 97% | 36% | 68% | 90% | 0.001 |
RF present | 77% | 36% | 63% | 53% | NS |
CRP > 18 | 37% | 72% | 100% | 51% | 0.002 |
ESR1 > 32 | 89% | 40% | 67% | 71% | 0.014 |
ANA | 20% | 68% | 51% | 45% | NS |
AKA | 65% | 68% | 74% | 59% | 0.01 |
Age > 50 | 29% | 80% | 67% | 44% | NS |
Duration > 6m | 97% | 8% | 60% | 67% | NS |
Smoking | 9% | 92% | 60% | 42% | NS |
Larsen score ≥35 | 80% | 48% | 68% | 63% | 0.02 |
HLA-DRB1*01 | 40% | 48% | 51% | 36% | NS |
HLA-DRB1*04 | 48% | 84% | 81% | 54% | 0.009 |