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Table 1 Arterial blood gas analysis before and after stopping salbutamol. The patient's clinical condition and blood gases improved dramatically after cessation of salbutamol. ABGs after 11 hours and 48 hours post-withdrawal of salbutamol are shown.

From: A case of lactic acidosis complicating assessment and management of asthma

Time/Date pH PaCO2 PaO2 HCO3 BE Lactate PEFR Symptoms/Treatment
11/1/06
21.20 hrs
7.39 3.03 KPa 20.5 KPa 13.6 mmol/l -11 mmol/l 14.6 mmol/l 230 L/min Minimal wheeze, SOB+ Reduced dose of Salbutamol
11/1/06
24.00 hrs
7.32 3.01 KPa 18.6 KPa 11.7 mmol/l -14 mmol/l 11.06 mmol/l 240 L/min No wheeze, hyperventilation+
12/1/06
3.00 hrs
7.28 2.29 KPa 11.4 KPa 8.3 mmol/l -19 mmol/l 15.2 mmol/l 230 L/min SOB+++, hyperventilation
12/1/06
7.00 hrs
7.3 2.13 KPa 13.8 KPa 8.0 mmol/l -18 mmol/l 10.09 mmol/l 300 L/min Minimal wheeze Nebulised salbutamol discontinued
12/1/06
23.00 hrs
7.43 3.46 KPa 12.3 KPa 17.6 mmol/l -7 mmol/l 6.3 mmol/l 300 L/min No wheeze Continued improvement
14/1/06
10.00 hrs
7.53 3.39 KPa 9.6 KPa 21.0 mmol/l -2 mmol/l 1.1 mmol/l 320 L/min Discharged to ward.