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Table 1 Arterial blood gas analysis before and after stopping salbutamol. The patient's clinical condition and blood gases improved dramatically after cessation of salbutamol. ABGs after 11 hours and 48 hours post-withdrawal of salbutamol are shown.

From: A case of lactic acidosis complicating assessment and management of asthma

Time/Date

pH

PaCO2

PaO2

HCO3

BE

Lactate

PEFR

Symptoms/Treatment

11/1/06

21.20 hrs

7.39

3.03 KPa

20.5 KPa

13.6 mmol/l

-11 mmol/l

14.6 mmol/l

230 L/min

Minimal wheeze, SOB+ Reduced dose of Salbutamol

11/1/06

24.00 hrs

7.32

3.01 KPa

18.6 KPa

11.7 mmol/l

-14 mmol/l

11.06 mmol/l

240 L/min

No wheeze, hyperventilation+

12/1/06

3.00 hrs

7.28

2.29 KPa

11.4 KPa

8.3 mmol/l

-19 mmol/l

15.2 mmol/l

230 L/min

SOB+++, hyperventilation

12/1/06

7.00 hrs

7.3

2.13 KPa

13.8 KPa

8.0 mmol/l

-18 mmol/l

10.09 mmol/l

300 L/min

Minimal wheeze Nebulised salbutamol discontinued

12/1/06

23.00 hrs

7.43

3.46 KPa

12.3 KPa

17.6 mmol/l

-7 mmol/l

6.3 mmol/l

300 L/min

No wheeze Continued improvement

14/1/06

10.00 hrs

7.53

3.39 KPa

9.6 KPa

21.0 mmol/l

-2 mmol/l

1.1 mmol/l

320 L/min

Discharged to ward.