Parameter | Level | Normal |
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TSH | 13.83 mIU/L | 0.30 – 3.94 |
T3 | 1.89 pg/mL | 2.42 – 4.36 |
ACTH | 1601 pg/mL | 5.0 – 47.0 |
Hematocrit | 29.7% | 37 – 52 |
Hemoglobin | 9.9 g/dL | 12 – 18) |
Immunoglobulin G | 4040 mg/dL | 751 – 1560 |
Kappa light chains | 48.7 mg/dL | absent |
Direct Coombs' | positive | negative |
Beta-2 microglobulin | 4.2 mg/L | 1.0 – 1.9 |
D-dimer | 2527 ng/ml | <500 |
Factor V Leiden mutation | heterozygote | absent |
ANA | > 1/1280 "speckled" | absent |
RNP/Sm | positive | negative |
SS-A/Ro | positive | negative |
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Test results within normal range: electrolytes (including calcium), glucose, kidney and liver function tests, white blood cell count with differential and platelets, free T4, IgM, IgA, indirect Coombs' test, erythrocyte sedimentation rate, C-reactive protein, troponin T; global coagulation parameters; urine analysis, urinary free lambda light chains; anti-extractable nuclear antigens antibodies (SS-B/La, Scl-70 and Jo-1), anti-dsDNA; anti-mitochondrial (AMA), anti-neutrophil cytoplasmic (ANCA) against myeloperoxidase (MPO) and proteinase-3 (PR3), anti-liver kidney microsomal, anti-parietal cell, anti-transglutaminase IgA and IgG, and anti-cardiolipin IgG and IgM antibodies; rheumatoid factor; angiotensin converting enzyme; complement levels C3 and C4; candida culture, serology on single determination for hepatitis viruses A, B and C, human immunodeficiency virus antigen/antibody, cytomegalovirus, herpes simplex virus-1 and -2, and varicella-zoster virus. Elevated ACTH reduced within days to normal values upon administration of increased doses of cortisone acetate resulting in cortisol levels of around 400 ng/mL (normal range: 65 – 250).
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Abbreviations: ANA, antinuclear antibodies; RNP/Sm, combined nuclear ribonucleoprotein Smith antigen.