The impact of obstructive sleep apnea variability measured in-lab versus in-home on sample size calculations

Table 1 Sample sizes required to provide nominal statistical power for 50% treatment effect within subject.

	ARES		PSG
Assumption	1-β = .80	1-β = .90	1-β = .80	1-β = .90
No bias, no reliability	24	31	57	76
No bias, observed reliability	10	13	27	35
Observed bias, no reliability	26	34	3,499	4,684
Observed bias, observed reliability	11	14	1,541	2,062

Assumed α = .05 *Nearest whole number sample size to generate, at minimum, the nominal value.