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Table 4 Results of Fung et al., 2003, meta-analysis.

From: Preoperative gemcitabine based chemo-radiotherapy in locally advanced non metastatic pancreatic adenocarcinoma

No of trials

regimens

No of patients

Average median an survival(months)

Hazard ratio

p-value

9

Best supportive care vs.

5-FU based combinations

434

262

3.87

6.38

0.53

<0.0001

7

5-FU/other agent alone vs.

5-FU based combination

428

414

5.23

4.98

0.88

0.1

3

5-FU based combination vs.

5-FU based combination

121

121

3.75

4.38

0.85

0.25

1

5-FU vs.

Gemcitabine

63

63

4.41

5.65

0.56

<0.005

2

Miscellaneous new agent vs.

Gemcitabine

241

242

3.70

6.08

0.61

<0.0001

7

Gemcitabine vs.

Gemcitabine based combination

758

745

6.62

6.98

0.92

0.15