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Table 4 Results of Fung et al., 2003, meta-analysis.

From: Preoperative gemcitabine based chemo-radiotherapy in locally advanced non metastatic pancreatic adenocarcinoma

No of trials regimens No of patients Average median an survival(months) Hazard ratio p-value
9 Best supportive care vs.
5-FU based combinations
434
262
3.87
6.38
0.53 <0.0001
7 5-FU/other agent alone vs.
5-FU based combination
428
414
5.23
4.98
0.88 0.1
3 5-FU based combination vs.
5-FU based combination
121
121
3.75
4.38
0.85 0.25
1 5-FU vs.
Gemcitabine
63
63
4.41
5.65
0.56 <0.005
2 Miscellaneous new agent vs.
Gemcitabine
241
242
3.70
6.08
0.61 <0.0001
7 Gemcitabine vs.
Gemcitabine based combination
758
745
6.62
6.98
0.92 0.15