Table 1 Binding of integrin-derived peptides to midkine
From: Midkine inhibitors: application of a simple assay procedure to screening of inhibitory compounds
Name | Sequence | Origin | Expected structure | Binding constant to midkine (μM) |
|---|---|---|---|---|
KQ9 | KQNQVKFGS | α4 247-255 | α-helix | 0.20 |
AM7 | AMETNLV | α4 359-365 | β-sheet | 0.95 |
MQ7 | MQSTIRE | α4 335-341 | β-sheet | 0.23 |
TF8 | TFSQRIEG | α4 419-426 | β-sheet | 0.14 |
KA11 | KANAKSCGECI | β1 29-39 | α-helix | 0.27 |
IE15 | IENPRGSKDIKKNKN | β1 80-94 | β-sheet | 0.30 |
PA9 | PAKLRNPCT | β1 200-208 | α-helix | 0.45 |