Table 2 Inhibitory activities of synthetic peptides and low molecular weight compounds to midkine-dependent migration.
From: Midkine inhibitors: application of a simple assay procedure to screening of inhibitory compounds
Materials | Concentration | Migration activity (%) |
|---|---|---|
None | 100 | |
Peptides | ||
YK12 | 1 mg/ml | 44.0 ± 10.5 |
GT11 | 1 mg/ml | 156 ± 6 |
QE10 | 1 mg/ml | 99.5 ± 10.6 |
KQ9 | 1 mg/ml | 107 ± 15 |
AM7 | 1 mg/ml | 99.5 ± 6.9 |
MQ7 | 1 mg/ml | 107 ± 2 |
TF8 | 1 mg/ml | 105 ± 24 |
KA11 | 1 mg/ml | 43.7 ± 12.8 |
IE15 | 1 mg/ml | 113 ± 10.1 |
PA9 | 1 mg/ml | 69.4 ± 46.1 |
Low molecular weight compounds | ||
Compound I | 0.146 mg/ml | 43.8 ± 10.2 |
Compound II | 0.10 mg/ml | 53.6 ± 4.1 |