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Figure 4 | International Archives of Medicine

Figure 4

From: LDLR-Gene therapy for familial hypercholesterolaemia: problems, progress, and perspectives

Figure 4

Schematic representation of the improved retrovirus three plasmid co-transfection system. Viral genome is segregated into three expression plasmids; the vector genome, the Gag/Pol expressing plasmid, and the envelope expressing plasmid. For generation of viral particles, these plasmids are co-transfected into the HEK 293 producer cells, and virus is released into the supernatant.

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