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Table 1 Chemotherapy protocols.

From: Treatment results and prognostic factors of pediatric neuroblastoma: a retrospective study

OPEC regimen Dose Route and duration of administration Timing
Vi Vincristine 1.5 mg/m2 i.v. Day 1
Cisplatin 80 mg/m2 i.v. (6 hours infusion) Day 2
Etoposide 200 mg/m2 i.v. (2 hours infusion) Day 4
Cyclophosphamide 600 mg/m2 i.v. (2 hours infusion) Day 1
Alternating every 3 weeks with OJEC regimen    
Vincristine 1.5 mg/m2 i.v. Day 1
Carboplatin 500 mg/m2 i.v. (6 hour infusion) Day 1
Etoposide 200 mg/m2 i.v. (2 hours infusion) Day 1
Cyclophosphamide 600 mg/m2 i.v. (2 hours infusion) Day 1