Figure 4From: Midkine as a factor to counteract the deposition of amyloid β-peptide plaques: in vitro analysis and examination in knockout mice RT-PCR analysis of the gene expression in the brain. Aβ-related gene expression was examined using the brain of WT, MKKO, PTNKO, and DKO mice at 2 months (2M) and 15 months (15M) of age. APP: amyloid precursor protein, ApoE: apolipoprotein E, Psn-1: presenilin 1, Nct: nicastrin, Bace-1: β-secretase 1, Ide: insulin degrading enzyme (insulysin), Mme: neprilysin. *: increased expression.Back to article page