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Table 1 Clinical, demographic and laboratory findings of the 3 patients

From: Gastrointestinal involvement revealing Henoch Schonlein purpura in adults: Report of three cases and review of the literature

Feature Case 1 Case 2 Case 3
Age (years)/Gender 62/F 20/M 66/M
GI involvment Hematemesis/abdominal pain Severe abdominal pain/vomitting Colicky abdominal pain/vomiting.
Skin rash Lower limb and abdomen Lower limb Lower limb
Joints involved Joint tenderness Arthritis of the knee and ankles arthritis of the ankle
Delay between GI involvement and other symptoms 3 weeks 4 weeks 2 weeks
Haemoglobin (g/dL) 10.3 15.6 14.7
Total leucocyte count (/μL) 13.000 10.400 12.200
Platelet count (/μL) 343.000 360.000 371.000
ESR (mm/1st hour) 45 22 37
Urine microscopy Microscopc hematuria Normal Normal
24-hour urinary proteins 3.3 gr Nil Nil
Renal function Normal Normal Normal
occult blood stool tests positive Not done negative
Colonoscopy colic poliposis with moderate dysplasia on the biopsy. Not done Not done
CT of the abdomen Not done Normal Not done
Skin biopsy Leucocytoclastic vasculitis
Leucocytoclastic vasculitis
DIF: Ig A/C3
Leucocytoclastic vasculitis
DIF: Ig A/C3
Oesogastroduodenal endoscopy/Biopsy Cardial ulcer with stigmata of bleeding and purpuric lesions of the bulb and the duodenum/presence of leucocytoclastic vasculitis with intestinal metaplasia and Hp gastritis Antrite congestive with purpuric lesions of the bulb and the duodenum/presence of leucocytoclastic vasculitis with chronic and moderately active Hp antral gastritis Purpuric lesions of the bulb and ulcers of the DI and DII portion of the bulb/erosive duodenitis and leucocytoclastic vasculitis 1
Kidney biopsy Extracapillar glomerulonephritis with Ig A depositis in DIF Not done Not done
treatment Methylprednisolone pulse (1 g/day × 3 days) + oral prednisolone associated with cyclophosphamide pulse Colchicine®
Outcome Complete recovery Complete recovery Complete recovery
  1. ESR: erythrocyte sedimentation rate; HPE: histopathology; DIF: direct immunofluorescence; GI: Gastrointestial ; PPI: proton pump inhibitors; Hp: Helicobacter pylori