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Table 2 Clinical and laboratory findings of the admitted patients according to age (n = 373)

From: Pandemic 2009 H1N1 virus infection in children and adults: A cohort study at a single hospital throughout the epidemic

Age groups 0-15 y
(n = 217)
16-40 y
(n = 100)
41-64y
(n = 35)
≥ 65 y
(n = 21)
P
Clinical Characteristics      
   Age, mean (y) 6.2 ± 3.7 25.2 ± 7 51.9 ± 6.7 74 ± 5 < 0.001
   Male/female 132/85 45/55 14/21 5/16 < 0.001
   Duration of fever (d)      
Before admission 2.0 ± 1.9 2.0 ± 1.1 1.7 ± 1.5 1.5 ± 1.3 0.045
Total duration 2.3 ± 1.0 2.9 ± 1.3 3.0 ± 1.7 4.1 ± 3.0 < 0.01
   Oseltamivir, < 48 h* 205 (94) 89 (89) 29 (83) 15 (71) NS
   Hospitalisation (d) 4.9 ± 1.5 5.4 ± 2.2 5.2 ± 2.9 8.8 ± 5.1 < 0.001
   Pneumonia      
Number (%) 80 (37) 16 (16) 9 (29) 11 (52) NS
Male/female 60/20 4/11 4/5 3/8 < 0.001
   Underlying diseases 17 (7.8) 15 (15) 15 (42.9) 16 (76.2) < 0.001
Laboratory findings      
   Haemoglobin (g/dL) 12.6 ± 0.9 13.5 ± 2.1 13.1 ± 1.6 12.9 ± 1.4 < 0.001
   Leukocyte (×109/L) 7.4 ± 3.6 6.4 ± 2.6 6.8 ± 2.8 7.6 ± 3.2 < 0.001
Neutrophil (%) 63 ± 19 66 ± 15 71 ± 14 64 ± 17 NS
Lymphocyte (%) 27 ± 17 23 ± 13 20 ± 12 24 ± 14 0.037
Monocyte (%) 9 ± 4 8 ± 4 8 ± 4 9 ± 4 NS
   Platelet (×109/L) 230 ± 59 202 ± 46 204 ± 51 198 ± 55 0.001
   CRP (mg/dL) 1.6 ± 2.0 2.4 ± 3.8 3.8 ± 4.6 6.1 ± 6.9 < 0.001
   ESR (mm/h) 17 ± 12 19 ± 17 37 ± 22 42 ± 19 < 0.001
  1. CRP; C-reactive protein, ESR; erythrocyte sedimentation rate. NS, statistically non-specific
  2. * Number (%) of patients who received oseltamivir treatment within 48 h of fever onset