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Table 3 Microscopic features semi-quantitative components of acinar, stromal pancreatic histology of acinar, ducts and pancreatic lesions located in degrees in the year 1995 (n= 109) and 2010 (n = 20)

From: AIDS and the pancreas in the HAART era: a cross sectional study

  

Degree

 

Variable

Year

Absent

Light

Moderate

Intense

p*

Decreased zimogen granula

1995

52 (47,7%)

52 (47,7%)

5 (4,6%)

0 (0,0%)

< 0,001

 

2010

1 (5,0%)

9 (45,0%)

6 (30,0%)

4 (20,0%)

 

Dysplasia-like

1995

35 (32,1%)

48 (44,0%)

19 (17,4%)

7 (6,4%)

< 0,001

 

2010

19 (95,0%)

0 (0,0%)

0 (0,0%)

1 (5,0%)

 

Atrophy

1995

44 (40,4%)

45 (41,3%)

17 (15,6%)

3 (2,8%)

0,017

 

2010

2 (10,0%)

13 (65,0%)

3 (15,0%)

2 (10,0%)

 

Steatosis

1995

36 (33,0%)

43 (39,5%)

23 (21,1%)

7 (6,4%)

0,689

 

2010

7 (35,0%)

7 (35,0%)

6 (30,0%)

0 (0,0%)

 

Inflammation

1995

59 (54,1%)

39 (35,8%)

7 (6,4%)

4 (3,7%)

0,673

 

2010

12 (60,0%)

5 (25,0%)

2 (10,0%)

1 (5,0%)

 

Haemorrhage

1995

78 (71,6%)

26 (23,9%)

4 (3,7%)

1 (0,9%)

0,921

 

2010

14 (70,0%)

5 (25,0%)

1 (5,0%)

0 (0,0%)

 

Fibrosis

1995

67 (61,5%)

22 (20,2%)

16 (14,7%)

4 (3,7%)

0,173

 

2010

8 (40,0%)

6 (30,0%)

6 (30,0%)

0 (0,0%)

 

Stoppers

1995

107 (98,2%)

2 (1,8%)

0 (0,0%)

0 (0,0%)

0,026

 

2010

17 (85,0%)

3 (15,0%)

0 (0,0%)

0 (0,0%)

 

Necrosis

1995

91 (83,5%)

18 (16,5%)

0 (0,0%)

0 (0,0%)

0,057

 

2010

18 (90,0%)

1 (5,0%)

1 (5,0%)

0 (0,0%)

 

Apoptosis

1995

109 (100,0%)

0 (0,0%)

0 (0,0%)

0 (0,0%)

< 0,001

 

2010

4 (20,0%)

8 (40,0%)

7 (35,0%)

1 (5,0%)

 

Increased Islets

2010 1995

8 (40,0%) 109 (100,0%)

9 (45,0%) 0 (0,0%)

3 (15,0%)0 (0,0%)

0 (0,0%) 0 (0,0%)

< 0,001

Islets with

1995

109 (100,0%)

0 (0,0%)

0 (0,0%)

0 (0,0%)

0,023

dysplasia-like changes

2010

18 (90,0%)

2 (10,0%)

0 (0,0%)

0 (0,0%)

 
  1. (*) Descriptive level of probability of Fisher’s exact test.