Table 4 PANSS, GAF, and SAS at baseline and after six and twelve weeks of treatment

PANSS positive

Baseline

23.8 ± 5.12

26.0 ± 4.41

1.90

0.06

6 weeks

18.2 ± 5.90

21.3 ± 2.51

2.86

0.006

12 weeks

18.9 ± 7.84

15.3 ± 2.18

2.55

0.013

PANSS negative

Baseline

22.2 ± 8.51

21.3 ± 6.38

0.48

0.63

6 weeks

20.4 ± 8.28

18.9 ± 6.21

0.86

0.39

12 weeks

15.5 ± 7.39

11.6 ± 4.76

2.59

0.012

PANSS general psychopathology

Baseline

39.0 ± 11.01

43.4 ± 8.36

1.939

0.056

6 weeks

35.1 ± 11.30

37.3 ± 11.01

0.79

0.43

12 weeks

23.8 ± 6.24

27.7 ± 6.33

2.58

0.012

PANSS depression/anxiety

Baseline

10.18 ± 2.11

9.88 ± 1.92

0.6

0.55

6 weeks

9.88 ± 1.95

9.29 ± 1.64

1.53

0.183

12 weeks

9.56 ± 1.87

4.74 ± 1.50

11.92

<0.0001

PANSS total

Baseline

82.3 ± 21.88

90.8 ± 11.32

1.939

0.056

6 weeks

73.8 ± 19.50

77.6 ± 8.90

1.02

0.31

12 weeks

58.3 ± 16.59

54.8 ± 5.93

1.17

0.24

GAF

Baseline

32.4 ± 12.03

31.3 ± 7.36

0.47

0.63

6 weeks

39.5 ± 10.28

40.0 ± 5.69

0.29

0.77

12 weeks

45.7 ± 9.52

46.2 ± 6.17

0.26

0.79

SAS

Baseline

-

-

-

-

6 weeks

5.94 ± 1.83

0.18 ± 0.38

18.020

<0.0001

12 weeks

8.62 ± 2.08

0.26 ± 0.45

22.949

<0.0001